GB Sciences Inc
announced on Wednesday that its subsidiary GBS Global
Biopharma, Inc. filed a patent application for its chronic pain formulations
made using cannabis extracts.

The newly filed patent covers the proprietary cannabis-based
formulations that are designed using functional assay data and molecular
docking simulations. A lot of research and development is currently being poured
into the pursuit of new pain treatments which might help curb opioids addiction
and opioid-related deaths. 

Opioids are currently used to treat chronic pain but their
major disadvantage is that they are highly addictive. More than 1.7 Million
Americans are affected by opioid addiction and about 50,000 people die annually
from opioid-related causes such as overdose. GB Sciences’ new patent for
cannabis-based chronic pain treatment presents a chance to reduce and possibly
eliminate the need for opioids.

“Unlike others who are narrowly focused on using a very limited number of cannabinoids for the treatment of pain, we embraced the complexity of whole-plant cannabis extracts,” stated Dr. Andrea Small-Howard, the Chief Science Officer at GBS.

GB Sciences’ patent
promises to deliver pain relief alternatives without toxicity drawbacks

Dr. Andrea also noted that GBS developed complex
combinations of TRP ligands that are based on Cannabis and can desensitize
numerous TRP channels at the same time. The complex compounds are also designed
to perform effectively while at the same time avoiding the numbness and neural
toxicity that results from capsaicin-based pain relievers applied topically.

GBS has been working on the project together with its research
partners from Chaminade University. They are the first to model the cannabidiol
and myrcene putative TRPV1-binding sites. Cannabidiol and Myrcene are among the
active ingredients that GBS includes in the chronic pain-targeting complex

The development team also leveraged the information that
they secured from the TRPV1-binding pockets to identify the pain-relieving
advantages of the compounds. GB Sciences is one of the companies that have been
carrying out cannabis-related research to solve some of the common health
conditions. The recently filed patent therefore represents significant progress
not only for the company but also for the cannabis industry and also the health